Representative Matters
代表事项
REFERENZMANDATE
IPOs and Capital Markets
- Goldman Sachs as lead underwriter in Sarepta Therapeutics’ $575 million follow-on public offering
- Goldman Sachs as lead underwriter in Exscientia’s (United Kingdom) $510 million initial public offering and concurrent private placement
- Candel Therapeutics in its $72 million initial public offering
- Monte Rosa Therapeutics in its $256 million initial public offering
- Vaccitech plc (United Kingdom) in its $110 million initial public offering
- Goldman Sachs as lead underwriter in Omega Therapeutics’ $126 million initial public offering
- Goldman Sachs as lead underwriter in Ambrx’s $144 million initial public offering
- Goldman Sachs as lead underwriter in Valneva’s (France) $107 million initial public offering
- Goldman Sachs as lead underwriter in Taysha Gene Therapies’ $181 million initial public offering
- Goldman Sachs as lead underwriter in Harmony Biosciences Holdings’ $148 million initial public offering
- Goldman Sachs as lead underwriter in Pandion Therapeutics’ $135 million initial public offering
- CRISPR Therapeutics (Switzerland) in its $518 million, $315 million, $200 million and $130 million public follow-on offerings; its $97 million initial public offering and concurrent private placement; and its $350 million and $600 million at-the-market offerings
- Avadel Pharmaceuticals (Ireland) in its $65 million financing transaction and its $125 million follow-on public offering
- Black Diamond Therapeutics in its $231 million initial public offering and $150 million at-the-market offering
- HOOKIPA Pharma (Austria) in its $84 million initial public offering and its $81 million and $75 million follow-on public offerings; and its private placement of up to $35 million
- BioDelivery Sciences International in its $60 million follow-on public offering
- Broadfin Capital on its investment in BioDelivery Sciences International’s $50 million follow-on public offering
- Surface Oncology in its $120 million initial public offering
- Goldman Sachs as lead underwriter in Arvinas’ $120 million initial public offering and subsequent $115 million and $400 million follow-on public offerings
- Ra Pharmaceuticals in its $58 million public follow-on offering
Joint Ventures, M&A and Collaborations
- BioDelivery Sciences International in its definitive acquisition by Collegium Pharmaceutical for $604 million
- Vaccitech plc (United Kingdom) in its acquisition of Avidea Technologies for $40 million
- Trillium Therapeutics (Canada) in its acquisition by Pfizer for $2.3 billion
- BioDelivery Sciences International in its acquisition of U.S. commercial rights to Elyxyb from Dr. Reddy’s Laboratories
- CRISPR Therapeutics (Switzerland) in its amended collaboration with Vertex Pharmaceuticals to develop, manufacture, and commercialize CTX001
- Avadel Legacy Pharmaceuticals, a wholly-owned subsidiary of Avadel Pharmaceuticals (Ireland), on the sale of its hospital product assets for approximately $42 million
- BlueRock Therapeutics on its acquisition by Bayer AG for approximately $1 billion
- Ginkgo Bioworks on its collaboration with Synlogic to accelerate the expansion and development of Synlogic’s pipeline of Synthetic Biotic medicines using Ginkgo’s cell programming platform
- CRISPR Therapeutics (Switzerland) in an expanded collaboration with Vertex Pharmaceuticals to enhance its gene editing capabilities to develop novel therapies for Duchenne Muscular Dystrophy and Myotonic Dystrophy Type 1
- Arvinas on an agreement with Bayer to jointly launch Oerth Bio to leverage Arvinas’ PROTAC technology for agricultural applications
- BioDelivery Sciences International in its acquisition of U.S. commercial rights to Symproic from Shionogi
- ProKidney and its lead investor, Pablo Legorreta, founder and CEO of Royalty Pharma, in the acquisition of inRegen and Twin City Bio LLC for $62 million
- CRISPR Therapeutics (Switzerland) in its collaboration with ViaCyte focused on stem cell therapies for the treatment of diabetes
- Ginkgo Bioworks in its joint venture with Bayer (Joyn Bio) focused on plant microbiome with an initial investment of $100 million
- Ginkgo Bioworks in its $14 million partnership with Glycosyn to optimize and scale the production of human milk oligosaccharides (hMOS)
- Lysosomal Therapeutics in its exclusive option arrangement with Allergan plc with an upfront payment of $150 million
- Padlock Therapeutics in its sale to Bristol-Myers Squibb with $225 million in upfront and near-term payments
- F-star Alpha (United Kingdom) in connection with its exclusive option agreement with Bristol-Myers Squibb with payments of up to $475 million
- CRISPR Therapeutics (Switzerland) in its collaboration with Bayer (Casebia Therapeutics) valued up to $335 million up front
- Alkermes (Ireland) in the sale of its manufacturing facility and the manufacturing and royalty revenue associated with products manufactured at the facility and global rights to Recro Pharma, for $170 million
- Guerbet (France) in a $270 million acquisition of Mallinckrodt's Contrast Media and Delivery Systems business
Venture/Mezzanine Financings
- Wellinks in its $25 million Series C financing
- 5AM Ventures and Frazier Healthcare Partners as lead investors in the creation and $30 million financing of Radionetics Oncology
- Versant Ventures as lead investor in the $50 million Series A financing of iECURE
- Versant Ventures as lead investor in the $63 million Series A financing of Stablix Therapeutics
- Ecovative Design in its $60 million Series D financing
- Atlast Food Co. in its $40 million Series A financing
- Vaccitech Limited (United Kingdom) in its $168 million Series B financing
- 5AM Ventures as lead investor in the $70 million Series A financing of Ensoma
- 5AM Ventures as lead investor in the $78 million Series A financing and $120 million Series B financing of Artiva Biotherapeutics
- Monte Rosa Therapeutics in its $32.5 million Series A financing, $96 million Series B financing, and $95 million Series C financing
- Broadfin Capital as an investor in Sonendo’s $85 million financing
- Black Diamond Therapeutics in its $85 million Series C financing
- Century Therapeutics in its launch with $250 million in financing from Bayer, Versant Ventures and Fujifilm Cellular Dynamics Inc, to advance to multiple programs into the clinic for hematologic and solid malignancies
- HOOKIPA Pharma (Austria) in its $37.4 million (€33.2 million) Series D financing
- Pablo Legorreta, founder and CEO of Royalty Pharma, as lead investor in ITBMed’s (Sweden) $67 million equity financing round
- 5AM Ventures as lead investor in a $45 million Series A financing and $60 million Series B financing of Neurogastrx
- Versant Ventures in collaboration with Bayer Healthcare in launching BlueRock Therapeutics, a next-generation regenerative medicine company, with a Series A financing of $225 million
- CRISPR Therapeutics (Switzerland) in its $140 million Series B financing
Professional Experience
Prior to rejoining Goodwin in 2014, Mr. Puopolo was a shareholder at Greenberg Traurig in Boston, where he served as co-chair of its emerging technology group. He has been licensed (inactive) in Massachusetts as a certified public accountant.
