Press Release January 04, 2019

C4 Therapeutics Enters Strategic Collaboration with Biogen to Discover and Develop Potential New Treatments for Neurological Conditions

The Life Sciences team advised C4 Therapeutics (C4T) on its strategic collaboration agreement with Biogen to investigate the use of C4T’s novel protein degradation platform to discover and develop potential new treatments for neurological conditions, such as Alzheimer’s disease and Parkinson’s disease.

Under the agreement, C4T will provide expertise and research services in targeted protein degradation and Biogen will provide neuroscience expertise and drug development capabilities. Biogen and C4T will research potential targets together and Biogen will advance candidates for development and potential commercialization. Biogen will pay C4T up to a total of $415 million in upfront and potential future milestone payments plus potential future royalties. Biogen expects to record a research and development expense of $15 million to $25 million in the fourth quarter of 2018 related to this transaction.

C4 Therapeutics is pioneering a new class of small-molecule drugs that selectively target disease-relevant proteins for degradation using the innate machinery of the cell.

The Goodwin team included partner Lawrence Wittenberg.

For additional details on the collaboration, please read the press release.